CBD Oil Dosage – General Advice to Assess How Much CBD to Take

 

Disclosure: The following statements are not necessarily those of CannaDIST Inc., it's vendor, employees or affiliates. These statements were gathered from reliable sources on the internet and may not be those of the FDA or any other federal government agency. Use with your own risk and like ALWAYS SEEK YOUR MEDICAL PHYSICIANS ADVICE.

 

 

 0:    CannaDIST.net Home Page

 

1:    General CBD Information

 

2:    CBD Oil Dosing

 

3:     CBD Dosing

 

4:    Mayo Clinic Dosing and Advice

 

4:    Five things to know about CBDs

 

5:    CBD Wide range of medical Benefits

 

 

 

 

 

Even with the wave of states legalizing medical marijuana, many physicians are still reluctant to prescribe cannabinoids because they are not sure what dosages to prescribe. After all, most medical schools never cover CBD Cannabidiol in their pharmacology courses. Medical scientists are just now developing dosing schedules for medical marijuana, medicinal hemp and their extracts, including CBD.

 

CBD-rich hemp oil comes in various concentrations and forms, including liquid hemp oil, hemp oil as a thick paste, oil in capsules, sublingual tincture drops or sprays, salves for topical use, edibles as in candy or gum and CBD vapor from vaporizers similar to e-cigarettes.

 

Everyone Is Different

 

What you will find on this page is meant to be a guideline, a starting point of reference. The fact remains that everyone is in a different place and will react differently to their CBD dosage. As serving size or dosage of CBD differs for each person, it is best to start small and gradually increase until you experience the desired result.

 

CBD Brands Confusing Dosage

 

CBD oil brands create a lot of confusion for consumers because they all have different standards. Many of them recommend way too much as a “serving” and others recommend too little. Because of this lack of standard during our review of individual CBD products, CBDOilReview.org created the COR Serving Standard to make things simple:

 

CBDOilReivew.org (COR) Serving Standard is 25mg of CBD taken twice a day.

 

It is also recommended that you try increasing dosage every 3-4 weeks by 25mg until symptom relief. And to decrease amount of CBD with any worsening of symptoms.

 

CBD Oil Dosing

 

Concentrations vary between preparations, ranging from 1 mg per dose to hundreds of milligrams. This makes it easy for consumers to get the dosages they need in a form they find easy to use.

 

CBD Dosages

 

Mayo Clinic suggests CBD dosages on scientific research, publications, traditional use, or expert opinion. Cannabinoid dosages and duration of treatment depend largely on the disease.

 

How Much CBD Oil Should I Take?

 

To increase appetite in cancer patients: 2.5 milligrams of THC by mouth with or without 1 mg of CBD for six weeks

 

To treat chronic pain: 2.5-20 mg CBD by mouth for an average of 25 days

 

To treat epilepsy: 200-300 mg of CBD by mouth daily for up to 4.5 months

 

To treat movement problems associated with Huntington’s disease: 10 mg per kilogram of CBD by mouth daily for six weeks

 

To treat sleep disorders: 40-160 mg CBD by mouth.

 

To treat multiple sclerosis symptoms: Cannabis plant extracts containing 2.5-120 milligrams of a THC-CBD combination by mouth daily for 2-15 weeks. A mouth spray might contain 2.7 milligrams of THC and 2.5 milligrams of CBD at doses of 2.5-120 milligram for up to eight weeks. Patients typically use eight sprays within any three hours, with a maximum of 48 sprays in any 24-hour period.

 

To treat schizophrenia: 40-1,280 mg CBD by mouth daily for up to four weeks

 

To treat glaucoma: a single CBD dose of 20-40 mg under the tongue. Doses greater than 40 mg may actually increase eye pressure.

 

According to CannLabs, the nation’s top full-service testing lab for cannabis products, there is no established lethal CBD dose. Consumers should read product inserts carefully to ensure they are taking the right amount of CBD, and talk to the prescribing physician about any questions or concerns.

 

How to Use CBD Oil – How to Take CBD Oil

 

CBD is most commonly taken orally in a concentrated paste or drops/ tincture format. To take CBD oil first hold it under the tongue to be absorbed in the mouth prior to swallowing. This step is important because some of the CBD taken will be broken down by the digestive system. Other oral methods include capsules, mouth strips, and edibles such as chocolate bars. Many people also enjoy using CBD oil via vaporizers or inhalers as this is a near instant delivery method that can be quite effective. Others use CBD oil by taking it through the skin via lotions, balms, creams or patches. There are many ways to take CBD oil, what matters most is trying a few different approaches and seeing what works. Again, everyone is different.

 

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http://www.mayoclinic.org/drugs-supplements/marijuana/background/hrb-20059701

 

Marijuana (Cannabis sativa) MAYO CLINC

 

Dosing

 

The below doses are based on scientific research, publications, traditional use, or expert opinion. Many herbs and supplements have not been thoroughly tested, and safety and effectiveness may not be proven. Brands may be made differently, with variable ingredients, even within the same brand. The below doses may not apply to all products. You should read product labels, and discuss doses with a qualified healthcare provider before starting therapy.

 

Adults (18 years and older)

 

To treat amyotrophic lateral sclerosis (nerve cell disease), 10 milligrams of THC has been taken by mouth daily for two weeks.

 

To prevent nausea and vomiting caused by chemotherapy, five milligrams per meter squared of dronabinol (Marinol®) has been taken by mouth 1-3 hours before chemotherapy, then every 2-4 hours after chemotherapy, for a total of 4-6 doses daily. A dose of two milligrams of nabilone has been taken by mouth the night before chemotherapy, 1-3 hours before and after chemotherapy. A dose of 2-3 milligrams of nabilone has been taken by mouth 2-4 times daily. A dose of three milligrams of nabilone has been taken by mouth three times daily as a one-time dose, a four-day duration, and the duration of two cycles of chemotherapy. Cannabinoids have been taken by mouth over a 24-hour period as follows: 1-8 milligrams of nabilone daily as 1-4 milligrams daily, one milligram 3-5 times daily, or two milligrams 2-4 times daily or 24-50 milligrams per meter squared of dronabinol daily as 10 milligrams per meter squared 4-5 times daily, 12 milligrams per meter squared twice daily, or 15 milligrams twice daily. A dose of one milligram of nabilone has been taken by mouth 8-12 hours before chemotherapy, followed by 0.5-2 milligrams of nabilone 2-3 times daily after chemotherapy, depending on body weight. A dose of 10 milligrams per meter squared of THC has been taken by mouth two hours before and four, eight, 16, and 24 hours after chemotherapy. Cannabinoids have been injected into the muscle over the course of 24 hours in the form of 0.5-1 milligrams of levonantradol three times daily.

 

To treat atopic dermatitis (itchy, scaly skin rashes), hemp seed oil has been taken by mouth for 20 weeks.

 

To increase appetite in people with cancer, 2.5 milligrams of THC has been taken by mouth with or without one milligram of CBD for six weeks.

 

To treat chronic pain, cannabinoids have been taken by mouth in the form of capsules or sprayed into the mouth as THC, benzopyranoperidine (BPP), cannabidiol (CBD), nabilone, dronabinol, or synthetic nitrogen THC analogs (NIB), with doses of 2.5-20 milligrams for an average of 25 days. Cannabis-based medicines have been used for 1-6 weeks. Ajulemic acid has been used for one week. Doses of nabilone of 0.25-2 milligrams have been used daily for 4-6 weeks. Doses of smoked cannabis of 1-9.4 percent have been used for six hours to 14 days. Cannabis has been smoked 3-4 times daily for five days. Doses of dronabinol of 10-20 milligrams have been used daily for six hours to six weeks. In people with cancer, 5-20 milligrams of delta-9-THC has been taken by mouth daily, as have the following doses: 2-8 milligrams of nabilone by mouth daily; 0.25-1 milligram of nabilone by mouth daily for four weeks; 1-2 milligrams of nabilone twice daily for a year; 1-2 milligrams of nabilone twice at an eight-hour interval; and 0.5 milligrams of nabilone twice daily for seven days, followed by two milligrams daily for three weeks. A dose of 0.5-1 milligrams of nabilone has been taken twice daily. A dose of 10 milligrams of THC has been taken by mouth, increasing to a maximum tolerated dose for six weeks. A mouth sprayhas been used in divided doses of 2.5-120 milligrams for two weeks. Doses of Sativex® have been sprayed into the mouth, up to 48 sprays daily, for 1-2 weeks, then 10-15 sprays daily, or 4-8 sprays, with eight being the maximum one-time dose or within a three-hour period.

 

To improve appetite in people with cystic fibrosis (mucus buildup in the organs), a dose of 2.5 milligrams of dronabinol has been taken by mouth, increasing to a maximum of 10 milligrams daily for 1-6 months.

 

To treat dementia, 2.5 milligrams of dronabinol has been taken by mouth twice daily for six weeks.

 

To treat eating disorders, 7.5-30 milligrams of THC has been taken by mouth daily for four weeks.

 

To treat epilepsy, 200-300 milligrams of CBD has been taken by mouth daily for up to 4.5 months.

 

To improve fatty acid status, hemp seed oil has been taken by mouth.

 

To treat movement problems caused by Huntington's disease, 1-2 milligrams of nabilone has been taken by mouth daily for five weeks. A dose of 10 milligrams per kilogram of CBD has been taken by mouth daily for six weeks.

 

To treat sleep disorders, 40-160 milligrams of CBD has been taken by mouth.

 

To treat multiple sclerosis symptoms, 2.5 milligrams of dronabinol (Marinol®) has been taken by mouth daily, increasing to a maximum of 10 milligrams daily for three weeks. A dose of 15-30 milligrams of cannabis extract capsules has been taken by mouth in five-milligram increments, based on tolerance, for 14 days. Cannabis extracts, including Cannador®, have been taken by mouth for 2-4 weeks. Cannabis plant extracts containing 2.5-120 milligrams of a THC-CBD combination have been taken by mouth daily for 2-15 weeks. A mouth spray (Sativex®, containing 2.7 milligrams of THC and 2.5 milligrams of CBD) has been used at a dose of 2.5-120 milligrams in divided doses for up to eight weeks. Eight sprays within any three hours, up to 48 sprays in a 24-hour period, have been used. Sativex® has been sprayed into the mouth for 6-14 weeks.

 

As a nutritional supplement, 15-30 milliliters of hemp oil has been taken by mouth daily.

 

To treat schizophrenia, 40-1,280 milligrams of CBD has been taken by mouth daily for up to four weeks.

 

To treat Tourette's syndrome, gelatin capsules containing 2.5-10 milligrams of THC have been taken by mouth as a single dose. A dose of 2.5 milligrams of THC has been taken by mouth daily, increasing to 10 milligrams daily in 2.5-milligram intervals over a four-day time period for six weeks.

 

To treat rheumatoid arthritis, up to six sprays of Sativex® have been used once daily 30 minutes before bed for five weeks.

 

To treat glaucoma (increased eye pressure), a single dose of five milligrams of THC has been placed under the tongue. A dose of 20-40 milligrams of CBD has been placed under the tongue as a single dose; however, 40 milligrams appeared to increase eye pressure.

 

Children (under 18 years old)

 

There is no proven safe or effective dose for marijuana in children.

 

 

 

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5 Must-Know Facts About Cannabidiol (CBD)

·         HEALTH  TECH

·         — FEB 23, 2014

·         http://www.leafscience.com/2014/02/23/5-must-know-facts-cannabidiol-cbd/

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·          

Chemical structure of cannabidiol. (Photo:Wikimedia Commons)

Chemical structure of cannabidiol. (Photo:Wikimedia Commons)

CBD, or cannabidiol, is quickly changing the debate surrounding the use of marijuana as a medicine.

Most people have heard of a chemical called THC, which is the ingredient in marijuana that gets users high. But recently, attention has shifted to another compound in marijuana called CBD — and for good reason.

Because while doctors can’t seem to look past certain side effects of THC, CBD doesn’t appear to present that problem. On the other hand, evidence of CBD’s medical benefits continues to grow.

Here are five facts that you should know about this unique compound:

1. CBD is a key ingredient in cannabis

CBD is one of over 60 compounds found in cannabis that belong to a class of molecules called cannabinoids. Of these compounds, CBD and THC are usually present in the highest concentrations, and are therefore the most recognized and studied.

CBD and THC levels tend to vary among different plants. Marijuana grown for recreational purposes often contains more THC than CBD.

However, by using selective breeding techniques, cannabis breeders have managed to create varieties with high levels of CBD and next to zero levels of THC. These strains are rare but have become more popular in recent years.

2. CBD is non-psychoactive

Unlike THC, CBD does not cause a high. While this makes CBD a poor choice for recreational users, it gives the chemical a significant advantage as a medicine, since health professionals prefer treatments with minimal side effects.

CBD is non-psychoactive because it does not act on the same pathways as THC. These pathways, called CB1 receptors, are highly concentrated in the brain and are responsible for the mind-altering effects of THC.

A 2011 review published in Current Drug Safety concludes that CBD “does not interfere with several psychomotor and psychological functions.” The authors add that several studies suggest that CBD is “well tolerated and safe” even at high doses.

3. CBD has a wide range of medical benefits

Although CBD and THC act on different pathways of the body, they seem to have many of the same medical benefits. According to a 2013 review published in the British Journal of Clinical Pharmacology, studies have found CBD to possess the following medical properties:

Medical Properties of CBD

Effects

Antiemetic

Reduces nausea and vomiting

Anticonvulsant

Suppresses seizure activity

Antipsychotic

Combats psychosis disorders

Anti-inflammatory

Combats inflammatory disorders

Anti-oxidant

Combats neurodegenerative disorders

Anti-tumoral/Anti-cancer

Combats tumor and cancer cells

Anxiolytic/Anti-depressant

Combats anxiety and depression disorders

Unfortunately, most of this evidence comes from animals, since very few studies on CBD have been carried out in human patients.

But a pharmaceutical version of CBD was recently developed by a drug company based in the UK. The company, GW Pharmaceuticals, is now funding clinical trials on CBD as a treatment for schizophrenia and certain types of epilepsy.

Likewise, a team of researchers at the California Pacific Medical Center, led by Dr. Sean McAllister, has stated that they hope to begin trials on CBD as a breast cancer therapy.

4. CBD reduces the negative effects of THC

CBD seems to offer natural protection against the marijuana high. Numerous studiessuggest that CBD acts to reduce the intoxicating effects of THC, such as memory impairment and paranoia.

CBD also appears to counteract the sleep-inducing effects of THC, which may explain why some strains of cannabis are known to increase alertness.

Both CBD and THC have been found to present no risk of lethal overdose. However, to reduce potential side effects, medical users may be better off using cannabis with higher levels of CBD.

5. CBD is still illegal except from hemp oil.

Even though CBD shows much promise as a medicine, it remains illegal in many parts of the world. CBD is classified as a Schedule I drug in the United States and a Schedule II drugin Canada.

On the other hand, the U.S. Food and Drug Administration recently approved a request to trial a pharmaceutical version of CBD in children with rare forms of epilepsy. The drug is made by GW Pharmaceuticals and is called Epidiolex.

According to the company, the drug consists of “more than 98 percent CBD, trace quantities of some other cannabinoids, and zero THC.” GW Pharmaceuticals makes another cannabis-based drug called Sativex, which has been approved in over 24 countries for treating multiple sclerosis.

A patent awarded to the U.S. Health and Human Services in 2003 (US6630507) also covers the use of CBD as a treatment for various neurodegenerative and inflammatory disorders.

 

 

Current Cannabidiol Legal Status

One of the most common questions we are asked is… “is cbd oil legal?” This is a tricky question, because Cannabidiol comes in two main forms. Cannabidiol can come from medical marijuana plants or from industrially grown hemp plants. Both are varieties of Cannabis, but they are grown for different purposes, and each one comes with its own legal status.

In addition to the above complication, you must also consider your country or state to figure out whether Cannabidiol is legal in your area. But first, let’s discuss the two types of Cannabidiol.

Cannabidiol from Medical Marijuana

The first form of Cannabidiol is extracted from medical marijuana plants. These plants are grown to be high in CBD but have varying amounts of the psychoactive compound THC. They are sold to licensed dispensaries and prescribed by doctors for particular conditions in places where marijuana is regulated — like the US.

While medical marijuana is grown to be high in CBD for the treatment of specific ailments, the THC content can vary dramatically, sometimes getting as high as the CBD content The problem with medical marijuana (besides the possibility of getting a strain that is high in THC) is that it’s not currently legal everywhere. In the United States, you must be living in certain states and obtain a prescription from a doctor to receive medical marijuana.

This restriction has even caused people to move to other states simply to get their hands on Cannabidiol legally for their families.

Cannabidiol from Industrial Hemp

Cannabidiol oil that comes from industrial hemp plants, like the products found on our website, are a different story. The FDA of the United States considers hemp oil (and its derivative CBD) to be a dietary supplement (not a medication), since they are made from industrial hemp plants.

If you live in the US, this means you don’t need a prescription and can legally purchase and consume Cannabidiol in any state.

Cannabidiol from industrial hemp also has the added benefit of having virtually no THC. This is why it’s not possible to get “high” with our products. There simply isn’t enough THC.

Is Cannabidiol Legal in My Country?

If you live in the US, the legal status is clear. Cannabidiol made from industrial hemp is legal to purchase and consume in any state. However, if you obtain Cannabidiol from medical marijuana, you must be located in a state in which medical marijuana has been legalized.

Unfortunately, outside of the United States the legal status is more confusing. Since regulations can vary for each country, we recommend that you reach out to your country’s customs department. Ask if you can import dietary supplements from the US. If you are allowed to do this, then you should be good to receive our products.

Will Cannabidiol Remain Legal?

While no one can answer this question with absolute certainty, recent studies indicate that CBD might have no negative side effects at all. Until research proves otherwise, the legal status of Cannabidiol is safe and will remain unchanged for the foreseeable future. Therefore, it seems that you can safely consume CBD without worry as long as it contains only traces amounts of THC (like CBD Supplements made from hemp not marijuana).